Scale & history
~20,000 breast‑cancer samples with longitudinal clinical context, including cohorts back to 2008 — enabling retrospective performance assessment of candidate panels.
The MultiOmics Biobank is a longitudinal breast‑cancer resource enabling rapid, retrospective discovery and validation of microRNA‑based diagnostic panels. With samples reaching back to 2008, researchers can test candidate molecular signatures against known outcomes before prospective studies.
~20,000 breast‑cancer samples with longitudinal clinical context, including cohorts back to 2008 — enabling retrospective performance assessment of candidate panels.
The DNA consent pathway was originally developed at Baylor. Samples and data are maintained by MultiOmics with consent‑based access controls and participant protection.
Blood‑based materials suitable for microRNA profiling. Where available, paired tissue or additional biospecimens support biology‑aware modeling.
Longitudinal context (diagnosis, subtype, imaging confirmation, and time‑to‑event where available) supports rigorous label definition. Datasets are de‑identified prior to release.
Identify and refine candidate microRNA signatures, optimize normalization, feature selection, and modeling approaches.
Evaluate sensitivity, specificity, AUC, and subgroup performance using historical samples with known outcomes — reducing risk ahead of prospective studies.
All access follows informed‑consent pathways with strict data‑minimization and privacy safeguards. Only de‑identified outputs leave MultiOmics environments.
Requests undergo documented review for scientific merit, feasibility, and ethical compliance. IRB documentation required when applicable.
Academic, clinical, or industry researchers working on diagnostic discovery, validation, or clinical‑utility studies — especially early detection and dense‑breast challenges.
Both may be supported depending on consent scope. Raw data for discovery; processed outputs for validation.
Timelines vary with study complexity. Validation‑focused work is generally faster than multi‑arm discovery projects.